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Molecular Imaging

PSMA PET-guided radiotherapy shows promise
By Will Morton
A trial demonstrated that radiotherapy informed by PSMA-PET led to improved outcomes in prostate cancer patients.
October 3, 2025
Prostate Imaging
PET reveals mechanism underlying brain fog in long COVID
By Will Morton
Brain regions where C-11 K-2 radiotracer was increased were negatively correlated with long-COVID patients’ performance on cognitive tests.
October 2, 2025
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SpectronRx’s Ac-225 boosted for use in Canada
By AuntMinnie.com staff writers
Ac-225 is a highly sought-after alpha-emitting isotope that shows promise for targeted cancer therapy.
October 1, 2025
Isotopes1
NAPT survey results show promise for proton therapy adoption
By Amerigo Allegretto
Proton therapy continues to experience increased clinical use, but barriers to care continue to limit its potential.
September 29, 2025
Survey Form 400
CPDC launches Cadena Research for radiopharmaceutical development
By AuntMinnie.com staff writers
The CPDC has launched Cadena Research, a new preclinical CRO offering support for early-stage radiopharmaceuticals.
September 29, 2025
Radiotherapy2 400
Case report: Pluvicto as a first-line treatment in late-stage prostate cancer
Since 1996, the patient continually declined androgen deprivation therapy, chemotherapy, and local therapy to the prostate gland.
September 26, 2025
Burden of PSMA-expressing prostate cancer before and after treatment with two cycles of Lu-177 PSMA-617. (A and B) Reduction in overall disease burden is evident after treatment. Avidity of patient’s primary prostate tumor and his osseous metastasis shown before (C) and after (D) treatment.
Lantheus and GEHC to launch PET agent for prostate imaging in Japan
By AuntMinnie.com staff writers
GEHC will draw on its manufacturing network and R&D expertise following its acquisition in March 2025 of Nihon Medi-Physics.
September 24, 2025
Prostate Imaging
NorthStar partners with Univ. of Wisconsin on radiopharma research
By AuntMinnie.com staff writers
The multiyear project furthers the goal of turning southern Wisconsin into a nuclear medicine hub.
September 23, 2025
Ame 2018 12 11 00 02 7009 Atom Nuclear Lab 400
Adding MBI to DBT finds more breast cancers
By Amerigo Allegretto
Adding molecular breast imaging (MBI) to DBT screening leads to more invasive cancers detected in women with dense breasts.
September 23, 2025
Images in a 62-year-old woman who presented for screening. (A) Image from DBT screening (the synthesized 2D mediolateral oblique view of the left breast is shown) at year on was interpreted as negative and showing heterogeneously dense breast. (B) Image from molecular breast imaging screening (mediolateral oblique view) at year one reveals a 0.9-cm non-mass focal area of uptake in the left breast (arrow). (C) Targeted ultrasound scan (transverse image) shows a suspicious mass in the 3-o’clock position of the left breast, 4 cm from the nipple. Ultrasound-guided core biopsy and lumpectomy revealed a 0.9-cm grade 2 invasive ductal carcinoma, an estrogen receptor–negative, progesterone receptor–negative, human epidermal growth factor receptor 2–negative lesion, with two sentinel nodes negative (N0).
Radiation oncologists put RefleXion’s X1 system to the test
By Will Morton
A pilot study demonstrates the potential feasibility of using RefleXion's X1 unit in patients with prostate cancer.
September 19, 2025
An example of a typical BgRT plan: A) PET scan on diagnostic PET/CT and B) X1 PET-Linac for patient #15 with a PET avid rib metastasis with GTV size= 3.1 cc, PTV = GTV + 5mm, BTZ (biological tracking zone) = PTV + 5 mm, AC = 14.33 kBq/mL and NTS = 21.04. Red, magenta, and green contours represent GTV, PTV, and BTZ. C) Dose distribution and D) bounded-DVH of a BgRT plan are displayed for the same patient. The bounded Dose-Volume Histogram (DVH) models variations in BgRT delivery, encompassing fluctuation in target background signal variation, target localization and dose delivery uncertainties.
4 nuclear medicine societies publish consensus statement on MPI
By AuntMinnie.com staff writers
Four nuclear medicine societies have issued a new guideline for F-18 flurpiridaz PET myocardial perfusion imaging (MPI).
September 18, 2025
Nuclear Medicine Gamma Camera 400
Contineum Therapeutics highlights data from PET drug trial
By AuntMinnie.com staff writers
Contineum Therapeutics has reported successful results from its Pipe-791 Phase 1b PET trial.
September 18, 2025
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