Clinical News

ARRS: Mobile mammo boosts breast screening, no-show rate still high
By Amerigo Allegretto
Free mobile screening mammography improves breast screening access for uninsured women, but doesn't lead to follow-up adherence.
April 30, 2025
Breast Screening Van 400 (1)
ARRS: How to manage 'controversial' high-risk breast lesions
By Amerigo Allegretto
Managing high-risk breast lesions with no consensus can be tricky, but breast radiologists can navigate this area.
April 30, 2025
Amie Lee, MD, presented at ARRS 2025 on managing 'controversial' high-risk breast lesions diagnosed on core needle biopsy. This slide outlines how to manage pleomorphic lobular carcinoma in situ (LCIS) via surgical excision.
AuntMinnie.com Women's Imaging Insider
By Amerigo Allegretto
Conference coverage from ARRS and AIUM annual meetings, a Supreme Court case, and breast cancer screening trends are on deck for this edition of the Women's Imaging Insider.
April 30, 2025
Preop MRI fails to deliver results for breast cancer subtype
Preoperative MRI didn't improve outcomes in women with HER2-positive and hormone receptor-negative breast cancer in a new study.
April 29, 2025
Images show a palpable mass in the left breast in a 55-year-old woman. (A) Mammography shows a 26-mm ill-defined mass with fine linear calcifications in the central portion of the left breast (arrows). (B) ultrasound shows a 23-mm hypoechoic mass with calcifications in the corresponding area accompanying palpability (between the arrows). (C) An axial, fat-saturated, contrast-enhanced T1-weighted MRI scan shows an 18-mm irregular heterogeneous enhancing mass in the left breast (arrows). After breast-conserving surgery, the final pathologic report confirmed a grade II estrogen receptor–negative, progesterone receptor–negative, human epidermal growth factor receptor 2–positive invasive ductal carcinoma. There was no lymphovascular invasion, and the resection margins were clear. The patient declined both adjuvant chemotherapy and radiation therapy due to psychologic distress. (D) 11 months later, surveillance ultrasound helped to detect a new 25-mm irregular hypoechoic mass at the 12-o’clock position in the left breast (arrows). A subsequent ultrasound-guided biopsy confirmed it as a recurrence of grade II invasive ductal carcinoma, maintaining the same receptor statuses. Images courtesy of the RSNA.
DL model can aid in diagnosing myocardial ischemia
By Will Morton
A deep-learning (DL) model can automatically measure myocardial blood flow on CT scans to help diagnose myocardial ischemia.
April 29, 2025
Representative images from diagnostic analysis of deep learning (DL)-based CT myocardial perfusion imaging (MPI). (A-D) Representative images in a 51-year-old woman with stable angina at presentation. (A) Curved planar reformation and (B) three-dimensional maximum intensity projection images show severe stenosis of the opening left anterior descending artery (arrow). (C) Fractional flow reserve (FFR) determined with invasive coronary angiography helps confirm that there was no hemodynamic significance of the opening left anterior descending artery lesion (arrow). (D) Dynamic CT MPI provided functional information to identify hemodynamically significant stenosis with reference to invasive FFR. Myocardial blood flow (MBF) derived from DL-based CT MPI revealed the absence of decreased myocardial perfusion of the left anterior descending artery territory (the areas outlined in black represent the myocardium subtended by the left anterior descending stenosis, and the color bar is a graphical scale that maps MBF ranges). (E-H) Representative images in a 62-year-old man with exertional chest pain at presentation. (E) Curved planar reformation and (F) three-dimensional maximum intensity projection images show moderate stenosis of the middle left anterior descending artery (arrow). (G) FFR determined at invasive coronary angiography helps confirm that the middle left anterior descending lesion was hemodynamically significant (arrow). (H) Dynamic CT MPI provided functional information to identify hemodynamically significant stenosis with reference to invasive FFR. DL-based CT MPI showed a reduction in MBF within the middle and basal anterior wall of the left anterior descending artery territory (the areas outlined in black represent the myocardium with decreased perfusion, and the color bar is a graphical scale that maps MBF ranges). MBFDL = MBF derived from the DL model.
ARRS: Radiologists can help PCPs boost lung cancer screening rates
By Kate Madden Yee
Radiologists can help boost lung cancer screening uptake by educating and supporting their primary care provider peers (PCP).
April 29, 2025
Lung Cancer
ARRS: 'Neurotheranostics' may be new frontier for nuclear medicine
By Will Morton
Advances in brain PET imaging combined with new treatments for Alzheimer’s have given rise to a new concept of "neurotheranostics."
April 29, 2025
A conceptual framework for neurotheranostics.
ARRS: Most women OK with mammo data used to assess cancer risk
By Amerigo Allegretto
Most women are comfortable with having their mammogram data be used to calculate lifetime breast cancer risk
April 28, 2025
Mammogram Breast
ARRS: MASLD diagnosis may be subject to racial factors
By Kate Madden Yee
The diagnosis of metabolic-associated steatotic liver disease (MASLD) may be influenced by ethnic, racial, and social factors.
April 28, 2025
Liver Disease Stages
Week in Review: Right to repair in NC | LCS for nonsmokers | Do women want mammo AI?
By Erik L. Ridley
Our most highly viewed articles last week included coverage of a right-to-repair bill for imaging equipment and the potential benefit of lung cancer screening for nonsmokers.
April 26, 2025
Mammo uptake among veterans on par with nonveterans
By Amerigo Allegretto
Female veterans are as likely to undergo screening mammography as nonveteran women.
April 25, 2025
Mammogram Patient
SPECT/CT predicts overall survival in Pluvicto patients
By Will Morton
New evidence supports using SPECT/CT scans along with serum PSA levels to evaluate early patient responses to Pluvicto treatment.
April 25, 2025
Patient examples of SPECT/CT and PET/CT RECIP 1.0. (A) SPECT and PET maximum-intensity projection (MIP) images in 74-year-old man with mCRPC. Serum PSA level at baseline was 449 ng/mL and slightly increased to 525 ng/mL after two cycles of Lu-177 PSMA. Eastern Cooperative Oncology Group (ECOG) score was 2 at baseline and increased to 3 after 2 cycles. The patient was classified by readers as RECIP-progressive disease on both SPECT and PET. Overall survival was 4.7 months. Two cycles of Lu-177 PSMA were administered. (B) SPECT and PET MIP images in 74-year-old man with mCRPC. Serum PSA level was 231 ng/mL at baseline and decreased to 12.5 ng/mL after 2 cycles of Lu-177 PSMA. ECOG score was less than 2 at baseline and after 2 cycles of Lu-177 PSMA. The patient was classified by readers as RECIP-partial response on both SPECT and PET. Overall survival was 14.3 months. Four cycles of Lu-177 PSMA were administered.
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