Jan Makela

[email protected]

Practice Management

Unlocking the potential of imaging in Alzheimer’s disease care

In the U.S., Alzheimer's disease cases are projected to rise to nearly 13 million, making effective imaging even more crucial for early identification and effective monitoring and treatment of the condition.

January 19, 2024

Brain Puzzle Night Sky

New imaging systems driven by AI will reduce radiologist burnout

Many radiologists are facing a tipping point when it comes to the overwhelming volume of imaging studies they face every day. Will new technologies such as artificial intelligence help? Jan Makela of GE Healthcare offers a perspective.

December 20, 2021

2019 11 14 18 07 2163 Computer Doctor Future 400

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Thumbnail 71 Year Old Patient With History Of Left Breast Invasive Lobular Carcinoma Mindul Thumbnail

ARRS: Breast RT doesn't impact presence of breast arterial calcifications

Cardiac Pet

IMV: PET/CT service contracts are a key aspect of system ownership

In her ARRS 2025 presentation, Amy Patel, MD, discussed ways that radiologists can be proactive in influencing legislation that addresses breast density. These include working with elected officials and joining medical societies, among others.

ARRS: Get involved with breast health advocacy

Lung Illustration Blue

ARRS: The state of lung imaging

At ARRS 2025, Dana Kong from Case Western Reserve University presented on breast cancer trends among women aged 40 years and younger. Among her team's findings, young women who had imaging prior to their cancer diagnosis had higher receptor status and underwent surgery more frequently than those with no prior imaging.

ARRS: Most women under 40 have no imaging before breast cancer diagnosis

ARRS: Breast RT doesn't impact presence of breast arterial calcifications

By Kate Madden Yee

May 2, 2025

Thumbnail 71 Year Old Patient With History Of Left Breast Invasive Lobular Carcinoma Mindul Thumbnail

IMV: PET/CT service contracts are a key aspect of system ownership

By Davin Korstjens

May 2, 2025

ARRS: Get involved with breast health advocacy

By Amerigo Allegretto

At ARRS 2025, Amy Patel, MD, discussed the need for advocacy to drive legislation on insurance coverage for women with dense breasts.

May 2, 2025

In her ARRS 2025 presentation, Amy Patel, MD, discussed ways that radiologists can be proactive in influencing legislation that addresses breast density. These include working with elected officials and joining medical societies, among others.

ARRS: The state of lung imaging

By Kate Madden Yee

There are a number of options for lung nodule imaging, and which to use depends on the patient.

May 1, 2025

Lung Illustration Blue

ARRS: Most women under 40 have no imaging before breast cancer diagnosis

By Amerigo Allegretto

Most young women who are diagnosed with breast cancer had no prior imaging performed.

May 1, 2025

At ARRS 2025, Dana Kong from Case Western Reserve University presented on breast cancer trends among women aged 40 years and younger. Among her team's findings, young women who had imaging prior to their cancer diagnosis had higher receptor status and underwent surgery more frequently than those with no prior imaging.

Controversy clouds nuclear medicine bill

Radiology societies and patient advocates are at odds over a bill in the U.S. Congress.

May 1, 2025

ARRS: Mobile mammo boosts breast screening, but no-show rate still high

By Amerigo Allegretto

Free mobile screening mammography improves breast screening access for uninsured women, but doesn't lead to follow-up adherence.

April 30, 2025

Breast Screening Van 400 (1)

ARRS: How to manage 'controversial' high-risk breast lesions

By Amerigo Allegretto

Managing high-risk breast lesions with no consensus can be tricky, but breast radiologists can navigate this area.

April 30, 2025

Amie Lee, MD, presented at ARRS 2025 on managing 'controversial' high-risk breast lesions diagnosed on core needle biopsy. This slide outlines how to manage pleomorphic lobular carcinoma in situ (LCIS) via surgical excision.

Preop MRI fails to deliver results for breast cancer subtype

Preoperative MRI didn't improve outcomes in women with HER2-positive and hormone receptor-negative breast cancer in a new study.

April 29, 2025

Images show a palpable mass in the left breast in a 55-year-old woman. (A) Mammography shows a 26-mm ill-defined mass with fine linear calcifications in the central portion of the left breast (arrows). (B) ultrasound shows a 23-mm hypoechoic mass with calcifications in the corresponding area accompanying palpability (between the arrows). (C) An axial, fat-saturated, contrast-enhanced T1-weighted MRI scan shows an 18-mm irregular heterogeneous enhancing mass in the left breast (arrows). After breast-conserving surgery, the final pathologic report confirmed a grade II estrogen receptor–negative, progesterone receptor–negative, human epidermal growth factor receptor 2–positive invasive ductal carcinoma. There was no lymphovascular invasion, and the resection margins were clear. The patient declined both adjuvant chemotherapy and radiation therapy due to psychologic distress. (D) 11 months later, surveillance ultrasound helped to detect a new 25-mm irregular hypoechoic mass at the 12-o’clock position in the left breast (arrows). A subsequent ultrasound-guided biopsy confirmed it as a recurrence of grade II invasive ductal carcinoma, maintaining the same receptor statuses. Images courtesy of the RSNA.

DL model can aid in diagnosing myocardial ischemia

A deep-learning (DL) model can automatically measure myocardial blood flow on CT scans to help diagnose myocardial ischemia.

April 29, 2025

Representative images from diagnostic analysis of deep learning (DL)-based CT myocardial perfusion imaging (MPI). (A-D) Representative images in a 51-year-old woman with stable angina at presentation. (A) Curved planar reformation and (B) three-dimensional maximum intensity projection images show severe stenosis of the opening left anterior descending artery (arrow). (C) Fractional flow reserve (FFR) determined with invasive coronary angiography helps confirm that there was no hemodynamic significance of the opening left anterior descending artery lesion (arrow). (D) Dynamic CT MPI provided functional information to identify hemodynamically significant stenosis with reference to invasive FFR. Myocardial blood flow (MBF) derived from DL-based CT MPI revealed the absence of decreased myocardial perfusion of the left anterior descending artery territory (the areas outlined in black represent the myocardium subtended by the left anterior descending stenosis, and the color bar is a graphical scale that maps MBF ranges). (E-H) Representative images in a 62-year-old man with exertional chest pain at presentation. (E) Curved planar reformation and (F) three-dimensional maximum intensity projection images show moderate stenosis of the middle left anterior descending artery (arrow). (G) FFR determined at invasive coronary angiography helps confirm that the middle left anterior descending lesion was hemodynamically significant (arrow). (H) Dynamic CT MPI provided functional information to identify hemodynamically significant stenosis with reference to invasive FFR. DL-based CT MPI showed a reduction in MBF within the middle and basal anterior wall of the left anterior descending artery territory (the areas outlined in black represent the myocardium with decreased perfusion, and the color bar is a graphical scale that maps MBF ranges). MBFDL = MBF derived from the DL model.

ARRS: Radiologists can help PCPs boost lung cancer screening rates

By Kate Madden Yee

Radiologists can help boost lung cancer screening uptake by educating and supporting their primary care provider peers (PCP).

April 29, 2025

ARRS: 'Neurotheranostics' may be new frontier for nuclear medicine

Advances in brain PET imaging combined with new treatments for Alzheimer’s have given rise to a new concept of "neurotheranostics."

April 29, 2025

A conceptual framework for neurotheranostics.

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