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TAG1, NRG Pallas to advance Pb-212 supply for cancer therapies

TAG1 and NRG Pallas have signed a letter of intent to jointly develop access to lead-212 (Pb-212) for cancer drug development across Europe.

This collaboration will combine TAG1's portable lead-212 generator with NRG Pallas' radium-224 (Ra-224) production capabilities.

The agreement builds on an existing supply arrangement under which NRG Pallas will continue to deliver high-purity Ra-224 to TAG1 through 2028. Together, the firms intend to supply preclinical and clinical quantities of lead-212 to cancer drug developers across Europe, including hospital-based adult and pediatric oncology programs.

The partnership is also exploring how its collaboration can support Lead4Life, a Dutch publicprivate initiative focused on developing lead-212-based radiopharmaceuticals and their supply chain.